Southampton (4-4-2): Alex McCarthy, Tino Livramento, Jan Bednarek, Mohammed Salisu, Romain Perraud, Theo Walcott, James Ward-Prowse, Oriol Romeu, Moussa Djenepo, Che Adams, Adam Armstrong
Manchester United (4-2-3-1): David de Gea, Aaron Wan-Bissaka, Victor Lindelof, Harry Maguire, Luke Shaw, Scott McTominay, Fred, Jadon Sancho, Bruno Fernandes, Paul Pogba, Mason Greenwood
Head-to-head (H2H)
Adapun head-to-head antara kedua belah pihak, Southampton dan Manchester United dalam berbagai pertandingan bisa dilihat di bawah ini:
2 Feb 2021: Manchester United vs Southampton 9 - 0
29 Nov 2020: Southampton vs Manchester United 2 - 3
13 Jul 2020 Manchester United vs Southampton 2 - 2
31 Agu 2019: Southampton vs Manchester United 1 - 1
2 Mar 2019 Manchester United vs Southampton 3 - 2
Southampton menang: 7